The Ultimate Anti-Aging Beauty Stack: Tremella, NMN+1200, CoQ10, Fisetin, Ergothioneine & Spermidine Explained

The Ultimate Anti-Aging Beauty Stack: Tremella, NMN+1200, CoQ10, Fisetin, Ergothioneine & Spermidine Explained

When it comes to supporting youthful skin, radiant glow and long-term vitality, the most meaningful changes start far beneath the surface. True beauty — plumpness, firmness, radiance — reflects how well your cells are functioning, repairing and renewing.

That’s why we created the Plant Rebels Anti-Aging Beauty Stack, combining four powerful ingredients that work together across hydration, energy production, antioxidant defence and cellular renewal:

Tremella • NMN+1200 • CoQ10 • Spermidine

Here’s how they work, and why they complement each other so well.

1. Tremella: Deep Hydration & Dewy Glow

Tremella holds up to 500× its weight in water, outperforming even hyaluronic acid in moisture retention.

Benefits:

  • Deep internal hydration

  • Plumper, dewier skin

  • Supports collagen pathways

  • Antioxidant protection

Tremella provides a foundation for natural, lasting glow.

2. NMN+1200: Cellular Energy, Repair & Longevity Support

NMN increases NAD⁺, essential for cellular energy, DNA repair and healthy aging.

Charava’s NMN+1200 adds two complementary compounds:

Resveratrol

Activates sirtuins — longevity pathways involved in cellular repair, inflammation management and DNA protection.

Pterostilbene

A more bioavailable, longer-lasting antioxidant than resveratrol → supports collagen integrity, protects against oxidative damage and improves cellular efficiency.

Together, these ingredients help strengthen skin function, boost cellular vitality and support healthy aging holistically.

3. CoQ10: Mitochondrial Energy, Whole-Body Vitality & Skin Health

CoQ10 fuels mitochondrial ATP production — essentially powering your cells.

Benefits Beyond Skin:

  • Improved energy + reduced fatigue

  • Supports heart & metabolic health

  • Strong antioxidant protection

  • Contributes to healthy cellular ageing

Beauty Benefits:

  • Supports collagen protection

  • Helps reduce dullness and early fine lines

  • Enhances skin regeneration

CoQ10 supports both external radiance and internal energy.

4. Fisetin: The Senolytic for Cellular Renewal & Healthy Aging

Fisetin is a flavonoid found in strawberries, apples and persimmons — but in supplements, it is used for its senolyticactivity.

What does senolytic mean?

As we age, some cells become “senescent”:
old, inactive cells that refuse to die and interfere with healthy cell function.

Fisetin helps the body clear out senescent cells, making room for healthier, younger cells to take over.

Longevity and wellness benefits

  • Supports deeper cellular rejuvenation

  • Helps regulate inflammation

  • Contributes to metabolic and cardiovascular health

  • May support cognitive clarity

Beauty-from-within benefits

  • Encourages healthier skin turnover

  • Supports smoother, more elastic skin

  • Helps reduce dullness linked to cellular aging

  • May support healthier hair growth

Fisetin is becoming one of the most exciting anti-aging nutrients because it targets aging at one of its root causes: the accumulation of senescent cells.

5. Ergothioneine: The “Cell Protector” Antioxidant Your Skin Loves

Ergothioneine is one of the most unique antioxidants found in nature — and your body treats it differently than almost any other nutrient:

Why it matters

  • The body has a dedicated transporter (OCTN1) just for ergothioneine

  • This transporter pulls ergothioneine directly into mitochondria, where oxidative stress is highest

  • Levels decline with age, stress, and environmental exposure

Benefits for longevity & whole-body wellness

  • Protects mitochondria — the energy centres of your cells

  • Supports healthy aging by reducing oxidative damage

  • Helps regulate inflammation and immune balance

  • May support cognitive resilience and cellular lifespan

Beauty-focused benefits

  • Improves skin’s ability to withstand UV stress

  • Supports brighter, calmer, more even-toned skin

  • Helps protect collagen from free radical damage

  • Acts as a “shield” against environmental aging

Ergothioneine is often called the antioxidant of the future because of how specifically the body uses it.

46 Spermidine: Cellular Renewal, Longevity & Beauty From Within

Spermidine stimulates autophagy, the body’s natural cellular clean-up and renewal process.

Whole-Body Benefits:

  • Supports cellular longevity

  • Improves metabolic and cardiovascular health

  • Supports cognitive function and clarity

  • Helps regulate inflammation

Beauty Benefits:

  • Enhanced skin firmness and elasticity

  • Brighter, smoother complexion

  • Supports healthy, fuller hair

Spermidine works at the deepest layer of cellular rejuvenation — supporting long-term health, vitality and glow.

Why These Ingredients Work Best Together

Tremella → Hydration + collagen support
NMN+1200 → Energy + longevity pathways
CoQ10 → Mitochondrial function + antioxidant defence
Spermidine → Cellular renewal + systemic wellness
Fisetin → Senolytic support + clearer, smoother skin
Ergothioneine → Mitochondrial protection + stress-resilient skin

Together, they form a routine that supports:

  • youthful, resilient skin

  • consistent energy

  • healthier aging

  • deeper cellular wellbeing

This is beauty that comes from true internal health — not temporary fixes.

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